|
Irritable Bowel Syndrome (IBS) is a combination of intestinal
symptoms where no detectable organic disease can be
found. This sets IBS apart from diseases such as Colitis
or Crohn’s disease where symptoms like inflammation
and ulceration show up on diagnostic tests. IBS therefore
becomes the diagnosis for those with moderate to serious
intestinal symptoms that don’t meet the criteria
for recognized intestinal diseases. IBS is a disorder
that interferes with the normal functions of the intestines
with symptoms that include cramping, abdominal pain,
bloating, constipation and diarrhea.
As
expected for a condition with subjective criteria, IBS
is a very common diagnosis. One in five Americans is
thought to meet the criteria for IBS and it is the most
commonly diagnosed gastrointestinal condition. It ranks
second only to the common cold as a cause of lost work
time. 30-50% of all referrals to gastroenterologists
are for IBS symptoms even though fewer than half of
IBS sufferers actually seek medical help. IBS is found
three times more often in women than in men and it usually
begins around age 20. Although many older adults have
irritable bowel syndrome, about 30% of IBS patients
notice a reduction in symptoms as they age. Over time,
less than 5 percent of those originally diagnosed with
IBS will be diagnosed with some other gastrointestinal
condition.
IBS
can cause a great deal of discomfort and distress but
unlike diseases such as ulcerative colitis and Crohn's
disease, IBS doesn't cause the serious inflammation
or changes in bowel tissue and it is not thought to
increase your risk of colorectal cancer. There do seem
to be links between IBS and leaky gut syndrome. The
effects of IBS on individual sufferers can range from
mild annoyance to a complete disruption of their lives.
Those with disabling degrees of IBS symptoms may be
unable to work, go to social events, or travel even
short distances.
There
are indications that a number of factors can contribute
to IBS including lifestyle and diet choices, stress
and an imbalance of intestinal flora. Stress has a widely
recognized negative affect on digestive processes. It
is likely that many people diagnosed with IBS have colons
that are more sensitive and that have a more intense
reaction to things that might not bother other people
including stress but also to large meals, medicines,
certain foods, caffeine and alcohol. The good news is
that the scientific and medical communities have recently
made significant progress in defining IBS and in combining
treatments to manage the symptoms. Most people can learn
to control their IBS symptoms through diet and lifestyle
improvements, stress management and medication.
Symptoms
of IBS
Diagnostic Criteria for IBS
Causes of IBS
IBS Relief & Treatment
Symptoms
Since IBS is a "functional" disorder with
symptoms described by the patient but no measurable
physiological abnormalities, doctors have had to agree
on a set of subjective criteria to determine if a person
is to be diagnosed with IBS. Abdominal pain and bowel
dysfunction are the primary symptoms but specific symptoms
may vary from person to person. While IBS is a chronic
condition for most people there are usually times when
symptoms are worse and times when symptoms improve or
even disappear.
Abdominal
Pain
Most characteristic of IBS is abdominal pain, typically
with cramps, varying in intensity and located in the
lower left abdomen. The nature, severity, and precise
location of pain can vary considerably from person to
person. Some people notice that emotional stress and
eating worsen the pain and that defecation relieves
the pain. Some women with IBS notice an association
between pain episodes and their menstrual cycle.
Altered
Bowel Habits
IBS affects the motility or movement of stool and gas
through the colon and how fluids are absorbed. When
diarrhea is the more common pattern, the condition is
called diarrhea predominant
IBS; when constipation
is the more common pattern, the condition is called
constipation dominant IBS. Many sufferers do however
experience alternating bouts of diarrhea and constipation.
When spasms push the stool through the colon too fast
for the fluid to be absorbed, diarrhea is experienced.
The diarrhea of IBS is usually characterized by frequent
loose stools of small to moderate volume. Bowel movements
usually occur during the daytime, and most often in
the morning or after meals.
Diarrhea is often preceded
by a sense of extreme urgency and followed by a feeling
of incomplete evacuation. Sometimes people with IBS
have a cramps and an urge to move their bowels but cannot
do so or pass mucus with their bowel movements. Diarrhea
occurring during sleep is very uncommon in IBS and should
alert to other possible diagnoses. When stool remains
in the colon for a long time, too much water is absorbed
from it. Then it becomes hard and difficult to pass
and constipation occurs. The constipation of IBS can
last from days to months. Stools are often hard and
pellet-shaped. Sometimes people experience a sensation
of incomplete evacuation, even when the rectum is empty.
This faulty sensation can lead to straining, sitting
on the toilet for prolonged periods of time and the
use of enemas and laxatives for relief.
Other
Gastrointestinal Symptoms
IBS can cause bloating or the condition of pressure
inside the abdomen from a build up of gas in the intestines.
Other gastrointestinal symptoms commonly experienced
by IBS patients include gas, belching, heartburn, acid
reflux, difficulty swallowing, an early feeling of fullness
with eating, and nausea.
Symptoms
Outside the Gastrointestinal Tract
Non-gastrointestinal symptoms may accompany the gastrointestinal
symptoms of IBS. These symptoms may include frequent
and urgent urination, painful menstruation, and sexual
problems.
Several
intestinal disorders have symptoms that are similar to
IBS. Examples include malabsorption (abnormal absorption
of nutrients), inflammatory bowel disease (such as ulcerative
colitis and Crohn's disease) and microscopic and eosinophilic
colitis (uncommon diseases associated with intestinal
inflammation). Bleeding, fever, weight loss, and persistent
severe pain are not symptoms of IBS and may indicate other
problems such as inflammation or rarely cancer. Research
has shown that very mild or hidden (occult) celiac disease
is present in a smaller group of people with symptoms
that mimic IBS. People with celiac disease cannot digest
gluten, which is present in wheat, rye, barley, and possibly
oats. Foods containing gluten are toxic to these people,
and their immune system responds by damaging the small
intestine. A blood test can determine whether celiac disease
is present.
Diagnostic
Criteria for IBS
Because there is no diagnostic test for IBS, experts
have set up guidelines on the (often subjective) types
and severity of symptoms to be used in making a diagnosis
if IBS. These guidelines are known as the Rome Diagnostic
Criteria for Irritable Bowel Syndrome and are now widely
accepted by the medical and scientific community.
The Rome Criteria allow for a diagnosis of IBS when
there are least 3 months of continuous or recurrent
symptoms of the following:
1. Abdominal pain or discomfort relieved with
defecation or associated with a change in frequency
of stool or associated with a change in consistency
of stool and
2. Two or more of the following at least on 1/4th of
occasions or days
- Altered stool frequency (for research purposes defined
as more than three bowel movements each day or less
than three bowel movements each week), or
- Altered stool form (lumpy/hard or loose/watery stool),
or
- Altered stool passage (straining, urgency, or feeling
of incomplete evacuation), or
- Passage of mucus, or
- Bloating or feeling of abdominal distention.
For additional information and resources
on the Rome criteria visit the website for the Rome
Committee at http://www.romecriteria.org
Causes
IBS symptoms cannot be
traced to a single organic cause. Some researchers think
IBS is caused by changes in the nerves that control
sensation or muscle contractions in the bowel. Others
believe the central nervous system may be affecting
the colon of individuals who are particularly sensitive.
Because women are two to three times more likely than
men to have IBS researchers believe that hormonal changes
may also play a role. For many women, symptoms are worse
during or around their menstrual periods. Research suggests
that people with IBS seem to have a colon that is more
sensitive and reactive than usual to a variety of things,
including certain foods and stress. Some evidence indicates
that the immune system, which fights infection, is also
involved. Likely contributing causes of IBS include:
Stress
and abnormal contractions of the colon
It is known that stress and anxiety have a number of
effects on the intestine and it’s logical that
stress would play a part in IBS symptoms. In fact, IBS
attacks are often triggered by major stress events such
as divorce, death of a loved one or a career change.
Like the heart and the lungs, the colon is controlled
by the autonomic nervous system through the many nerves
that connect it to the brain. The walls of the intestines
are lined with layers of muscle that contract and relax
as they move food from your stomach through the intestinal
tract to the rectum. In reaction to stressful events
the colon often either begins violent spasmodic contractions
(hence the older term "spastic colon" which
was once used to describe IBS) or slows down or stops
contracting.
When the contractions are stronger and
last longer than normal, food is forced through your
intestines more quickly causing gas, bloating and diarrhea.
When contractions are weaker, passage slows and stools
become hard and dry and constipation occurs. Some evidence
suggests that IBS is affected by the immune system,
which fights infection in the body. The immune system
is also affected by stress. For all these reasons, stress
management is an important part of treatment for IBS.
Food
allergies
Food intolerances are present in 50% to 65% of the patients
with IBS raising the possibility that IBS is caused
by food sensitivity or allergy. The best way to detect
an association between symptoms of IBS and food sensitivity
is to eliminate certain food groups systematically (a
process called an elimination diet) which is usually
best accomplished under the supervision of a doctor
or nutritionist. The most common reactions are to dairy
products and grains like wheat and corn. Other foods
that frequently trigger IBS sensitivity are citrus fruits,
chocolate, beans, cruciferous vegetables (such as broccoli,
cauliflower, brussels sprouts, and cabbage), stimulants
like caffeine and tobacco, depressants like alcohol
and non-nutritive sweeteners like Sorbitol and Xylitol
.
Intestinal
Flora Imbalance
The health of intestinal tract is maintained by disease
fighting beneficial bacteria. It is important to maintain
the ratio of beneficial (probiotic) bacteria to pathogenic
bacteria (approximately 80% or more to 20% or less).
When an imbalance occurs, pathogenic bacteria overgrow,
overwhelm beneficial bacteria and stop them from doing
their work and produce harmful substances that irritate
the lining of the intestines. This irritation can eventually
breach the integrity of the intestinal walls allowing
toxins to be absorbed into the bloodstream leading to
additional serious consequences.
Other
GI diseases
The development of IBS following severe gastrointestinal
infections (such as those caused by Salmonella or Campylobacter)
has been well recognized for many years. The mechanisms
by which the infections trigger the development of IBS
are not well understood.
Relief
& Treatment
It’s not surprising that no “cure”
has been found for IBS since it seems to be a collection
of syndromes with a number of contributing causes. The
first step in treating IBS may be close monitoring of
the symptoms, your daily habits, and any other factors
that may affect gastrointestinal function. It is strongly
advised to work closely with a health care provider
though many sufferers simply endure the symptoms because
of embarrassment. A variety of symptom related treatments
and therapies are available and they can be utilized
and combined to effectively reduce the pain and intestinal
distress and to effectively “manage” IBS.
Dietary
modification
People with IBS commonly describe food intolerances
and, for many people, careful eating reduces IBS symptoms.
Before changing your diet, the systematic elimination
of particular foods can be helpful to determine the
relationship between the food and symptoms. Keeping
a record of food intake and discomfort can help you
make effective changes to your diet. The danger in eliminating
foods in a nonsystematic way is that it can erroneously
lead people to eliminate important sources of nutrition
from their diet. In addition, unnecessary dietary restrictions
can further worsen the quality of life in patients who
already have enough to cope with.
Many doctors recommend the temporary
elimination of dairy products since lactose intolerance
is common and can cause symptoms similar to IBS or aggravate
IBS. People who avoid lactose should take dietary calcium
supplements. Several foods are only partially digested
in the intestines. When they reach the colon, further
digestion takes place by bacteria, which produce gas
as a byproduct of their digestion. As a result, these
foods can cause gas and cramps. The most common are
the legumes (such as beans) and cruciferous vegetables
(i.e., vegetables that have a cross at their base) such
as cabbage, brussels sprouts, cauliflower, and broccoli.
In addition, some patients have trouble with onions,
celery, carrots, raisins, bananas, apricots, prunes,
sprouts, and wheat. Digestive
enzyme supplements can help with the first stages
of digestion and probiotic
supplements can insure the bacterial balance necessary
to complete digestion.
High-fiber diets keep the colon mildly
distended, which may help prevent spasms. Some forms
of fiber also keep water in the stool, thereby preventing
hard stools that are difficult to pass. Doctors usually
recommend a diet with enough fiber to produce soft,
painless bowel movements. High-fiber diets may cause
gas and bloating, but these symptoms often go away within
a few weeks as your body adjusts. Whole grain breads
and cereals, fruits, and vegetables are good sources
of fiber but are not always convenient. Fiber supplements
and high fiber
meal replacers can be introduced in these cases.
Drinking six to eight glasses of plain
water a day is important, especially if you have diarrhea.
Drinking carbonated beverages, such as sodas, may result
in gas and cause discomfort. Chewing gum and eating
too quickly can lead to swallowing air, which again
leads to gas. Also, large meals can cause cramping and
diarrhea so eating smaller meals more often or eating
smaller portions should help IBS symptoms. It may also
help if your meals are low in fat and high in vegetables,
fruits and complex carbohydrates such as whole grain
breads and cereals.
Stress
management
Worry, anxiety and other mental stress are major components
in many IBS attacks. If possible, identify and avoid
stressors that make your IBS symptoms worse. Making
time to relax and spend quiet time alone can be therapeutic
and rejuvenating. Yoga and meditation have been used
for thousands of years to reduce stress. It is important
to prioritize your daily tasks and not to overload your
schedule. Besides improving your overall health, regular
exercise can provide benefits that are especially valuable
to people with IBS. It can help decrease feelings of
stress and may help simulate rhythmic contractions of
your intestines. Another stress reducing option is psychological
therapy including counseling, hypnosis therapy and cognitive
behavioral therapy. For stress caused by living with
IBS itself, participation to IBS support groups can
be very helpful.
Fiber
supplementation
As mentioned above it can be helpful to take a dietary
fiber supplement since it is often difficult to get
sufficient fiber in the diet, particularly when avoiding
foods known to increase intestinal gas. Fiber
supplementation or high
fiber meal replacers can relieve symptoms in some
people with IBS, particularly people who have combined
abdominal pain and constipation. Fiber supplements may
also be helpful in people with diarrhea predominant
IBS since it can improve the consistency of stools.
Dietary fiber supplements should be increased to the
prescribed dose over several weeks to help reduce the
symptoms of excessive intestinal gas, which can occur
in some people when beginning fiber therapy.
Probiotic
supplimentation
Studies indicate that lactobacillus bacteria even as
the only treatment can have a significant effect on
IBS symptoms (Treatment of Irritable Bowel Syndrome...American
Journal of Gastroenterology, 91: 1579-1585, 1966.).
As discussed throughout, pathogenic bacteria in the
intestinal system can be both a major causative factor
and the result of IBS symptoms. Probiotics are beneficial
bacteria that attack and reduce pathogenic bacteria
allowing for the restoration of intestinal balance necessary
to proper digestion. They also play a crucial role in
both the protection and regeneration of the intestinal
walls. Supplementation with an effective probiotic
is an essential part of effectively managing IBS and
IBS like symptoms.
Drugs
Although many drugs are available to treat the symptoms
of IBS, these drugs do not cure the condition and are
used primarily to support other types of treatment.
The choice among these drugs depends in part upon whether
the sufferer’s primary symptom is diarrhea, constipation
or abdominal pain. As a general rule, drugs are reserved
for patients whose symptoms have not adequately responded
to more conservative measures such as changes in diet
and fiber and probiotic supplementation. In those cases,
medicines to decrease diarrhea, tranquilizers or drugs
that control colon muscle spasms and reduce abdominal
pain may be prescribed. Where there is depression and
antidepressants are prescribed, they may also function
to relieve intestinal symptoms by inhibiting the activity
of neurons that control the intestines. In some cases,
drugs that affect the nervous system (anticholinergics)
are prescribed to relieve painful bowel spasms.
Herbs
and natural therapies
A number of herbal and natural therapies have been advocated
for the treatment of IBS including: peppermint oil,
slippery elm powder (for healing irritated tissues),
mint leaves, ginger, chamomile, evening primrose oil
and fennel seed.
Managing
IBS symptoms
Living with IBS presents daily challenges as the symptoms
may be painful or embarrassing and may seriously affect
the quality of life. Improvement may be the result of
gradual trial and error and your body likely won't respond
immediately to every change you make. Be confident though
that better control of IBS symptoms is very possible
with sustained lifestyle modification including: monitoring
and improving the diet (including enzyme supplementation
and when indicated fiber supplementation), stress management
and balancing intestinal flora through probiotic
supplementation.
|